Yes, you can wager using Bitcoin or altcoins when playing Crash games. The Crash game is unique, and it's primarily a pride of the BTC and crypto betting industry, thanks primarily to its provably fair concept that gets inspiration from the blockchain. In short, this game primarily supports Bitcoin and altcoins for bets and payments.
But don't worry if you don't have cryptos when you register in one of the betting sites that offer this game. Most crypto casinos feature an exchange that lets you swap your fiat currencies to cryptos or convert one crypto to another. Pasino Casino, for example, boasts an 'Exchange' feature under its Wallet. Here, you can swap your Bitcoin for Ethereum or trade any crypto for another.
On the window, you'll find information about the amount you'll get after the swap, subject to the asset's prevailing market price. If you don't have crypto, you can buy it in a reputable crypto exchange using your online bank, credit or debit card, or e-wallet.